This is an HTML version of an attachment to the Freedom of Information request 'Comunicaciones reinfecciones ECDC'.





tested two days following the re-exposure and, if negative, be tested again after a further two days.
If negative with two PCR tests, then the quarantine is lifted.
Due to the very limited number of reported cases of confirmed reinfection, it is not known what the
risk of reinfection is among individuals who previously had COVID-19, however it cannot be ruled out
[38]. Although there are no documented cases of onward transmission from a re-infected case,
knowledge on this is also still evolving. Risk assessment, including relevant laboratory investigations,
may be made for re-exposed cases, taking into account the overall immune status of a re-exposed
individual, the results of PCR and antibody testing, and the level of contact that the individual has
with vulnerable populations in order to assess the best method of managing and following them for
potential disease development and risk of further transmission. While low level of exposure, and a
negative PCR test, particularly in the context of a positive IgG test, may be considered indicators of
lower risk of developing infection, decisions on risk management need to take into account that the
evidence on the protective immunity and the correlates of antibody levels with viral clearance is
currently limited. Nonetheless, the testing of individuals that had a previous infection for SARS-CoV-
2, if they are again exposed to a COVID-19 case after their first episode of the disease, would not
only inform individual case assessments but also improve the current limited evidence-base on the
risks of re-infection.
The suggestions above are based on limited evidence which is expected to evolve. ECDC will
continue to reassess the evidence and update the options for response for re-infected cases as
additional evidence becomes available.
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