new Commissioner for Innovation and Youth. Building a true European research area is one of the most important challenge of European Union to stay competitive globally. So programming a great research and innovation agenda will be the key of the success of Horizon Europe. Inserm is strongly invoved in the consultations organised by the and Research. The institute is dedicated to biomedical research and human health, and is involved in the entire range of activities from the laboratory to the patient’s bedside. It also partners with the most prestigious research institutions in the world that are committed to scientific challenges and progress in these fields. Researchers of Inserm are involved in more than 90 projects in the Societal challenge one (Health, demographic change and well being) of Horizon 2020. So Inserm is the European leader organisation in this Societal challenge. Inserm research teams are also strongly participating in the Marie Sklodowska Curie programme to train and prepare the new generation of researchers. Finally, Inserm is strongly involved in the Joint Technology Initiative IMI2 and and is member of the EIT Health. So Inserm is strongly involved in Research dissemination and Innovation. The December 4th meeting will be the opportunity to talk about challenges of sustained and innovative health research in Europe and share Inserm's vision.